There are a multitude of studies on Medline regarding hyaluronic acid and a wide variety of environmental factors.
Hyaluronic acid becomes abnormally elevated in the skin of swine who have zinc deficiencies. Magnesium is needed for hyaluronic acid synthesis. Perhaps a lack of magnesium is one of the factors in some connective tissue disorders. Magnesium supplementation is an established treatment for many of the symptoms of connective tissue disorders, such as fibromyalgia, mitral valve prolapse and contractures.
Ascorbic acid can degrade hyaluronic acid. Estrogen treatment increases activity of hyaluronic acid. Estrogen is known to increase utilization of nutrients like magnesium and zinc - nutrients that are known to affect hyaluronic acid levels. Cigarette smoke is known to degrade hyaluronic acid.
In a study of rats, hyaluronic acid turnover and metabolism were affected by age, dietary composition, and caloric intake. If what rats ate affected their hyaluronic acid levels, then this may be a good clue that diet may well affect hyaluronic levels in humans, too. In another study on rats, hyaluronic acid deposition in rat cerebellum is affected by thyroid deficiency, thyroxine treatment and undernutrition. In a study of humans, hyaluronic acid levels were altered by physical activity and food ingestion.
Strep and staph bacteria emit an enzyme called hyaluronidase. Hyaluronidase is an enzyme which breaks down hyaluronic acid, thus allowing an entry point for the bacteria to enter the body. This may be why people may become hypermobile or develop heart aliments like mitral valve prolapse after illnesses such as rheumatic fever--because the hyaluronic acid in their connective tissue has been degraded by the bacteria that causes their illness. (See my section on "What Causes Mitral Valve Prolapse? Hyaluronic acid as a clue" for more on this topic.)
If animals that are genetically similar to humans such as rats can have reduced collagen levels and hyaluronic acid abnormalities from changes in their diets, then it would be logical to consider diet as a causative factor in people with the hyaluronic acid abnormalities.